Everything about Ovalocytosis totally explained
Ovalocytosis is an
inherited condition in which a person's
red blood cells, which are supposed to be round, instead have a slightly
oval or
elliptical shape (also known as hereditary elliptocytosis). This condition is associated with mild
hemolytic anemia. In severe cases, the disease may be treated by removal of the
spleen.
The term 'ovalocytosis' is most commonly used in reference to a particular subtype of hereditary elliptocytosis known as South-East Asian ovalocytosis, which is caused by a particular mutation in
Band 3, an erythrocyte membrane protein.
South-East Asian ovalocytosis is common in some communities in
Malaysia and
Papua New Guinea, as it confers some resistance to cerebral Falciparum
Malaria.
Further Information
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